Vet Wrap Podcast, Ep 16: Myths and Misconceptions! Why Vets Need to Rethink PPIs

Dr Kathryn Hogan (Internal Med Registrar) joins Dr Arthur House, to shed light on when PPIs really help—and when they don’t.

Kathryn takes us inside the data—and the fallout—of her PPI research. From microbiome disruption to rethinking prescribing habits, this is a must-listen for anyone who’s ever reached for omeprazole without a second thought.

CORRECTION:

During the episode, Dr Hogan mentions that metoclopramide dosing is 8 times higher when used as a CRI — this was incorrect. 👉 The correct figure is 12 times higher.

We’ve included references below for those wanting to explore further.

REFERENCES:

  1. ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats: https://onlinelibrary.wiley.com/doi/10.1111/jvim.15337
  2. Influence of metoclopramide on gastroesophageal reflux in anesthetized dogs: https://avmajournals.avma.org/view/journals/ajvr/67/1/ajvr.67.1.26.xml?tab_body=fulltext
  3. Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs: https://onlinelibrary.wiley.com/doi/10.1111/jvim.15383
  4. The Influence of Esomeprazole and Cisapride on Gastroesophageal Reflux During Anesthesia in Dogs: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1939-1676.2012.00929.x
  5. Comparative analysis of the effect of IV administered acid suppressants on gastric pH in dogs: https://onlinelibrary.wiley.com/doi/10.1111/jvim.15718
  6. Effects of ranitidine, famotidine, pantoprazole, and omeprazole on intragastric pH in dogs: https://avmajournals.avma.org/view/journals/ajvr/66/3/ajvr.2005.66.425.xml

 

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