SnorTox Clinical Trial for Brachycephalic Dogs

A Promising New Treatment for Flat-Faced Dogs Struggling to Breathe

Dr Arthur House and researchers are preparing for a larger clinical trial testing SnorTox, a treatment designed to improve breathing in brachycephalic (flat-faced) breeds. The treatment uses tetanus toxoid, the opposite of Botox, which contracts muscles instead of relaxing them. It’s injected under the tongue to help pull the larynx forward, improving airflow.

So far, the trial has only involved British Bulldogs, with promising results. The next step is to trial the treatment in smaller breeds — specifically two French Bulldogs, two Pugs, and two British Bulldogs — to evaluate safety and efficacy at a different body size.

Clinical trial details

• Free CT scans and drug administration
• Commitment to attend follow-up visits at 2 weeks and monthly for 3–6 months
• Treatment done under anesthesia/sedation
• Eligible dogs are those with moderate or severe airway disease. Dogs that have had previous surgery are eligible.

The treatment is considered an adjunct to surgery, but could be ideal for dogs where surgery isn’t advisable due to comorbidities.

The aim is for SnorTox to eventually be available to both specialists and general practitioners. The trial is open now, accepting referrals from both vets and the public.

Contact

VETS
Vets, please contact Dr Arthur House directly if you have a patient that may be a good candidate.
Dr Arthur House | arthur@penvetreferral.com.au

PUBLIC
For public enquiries, please phone our main reception number.